Publication List of 2013 / 2012 / 2011 / 2010 / 2009 or before (PDF)

Publication List (2014)

"Molybdenum-mediated desulfurization of thiols and disulfides"

Wang, Z.; Kuninobu, Y.; Kanai, M.
Synlett 2014, 25, 1869. DOI: 10.1055/s-0034-1378315

"A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less-Toxic Off-Pathway Amyloid-β Oligomers"

Arai, T.; Sasaki, D.; Araya, T.; Sato, T.; Sohma, Y.; Kanai, M.
ChemBioChem 2014, 15, 2577. DOI: 10.1002/cbic.201402430

"Copper-Mediated Direct C(sp3)-H and C(sp2)-H Acetoxylation"

Wang, Z.; Kuninobu, Y.; Kanai, M.
Org. Lett. 2014, 16,4790. DOI: 10.1021/ol5022542

"Chemoselective aerobic photo-oxidation of 9H-fluorenes for the synthesis of 9-fluorenones"

Kojima, M.; Oisaki, K.; Kanai, M.
Tetrahedron Lett. 2014, 55, 4736. DOI: 10.1016/j.tetlet.2014.06.038

"Reaction mediated artificial cell termination: control of vesicle viability using Rh(I)-catalyzed hydrogenation"

Komatsu, H.; Daimon, Y.; Kawakami, K.; Kanai, M.; Hill, J. P.; Ariga, K.
Phys. Chem. Chem. Phys. 2014, 16, 16454. DOI: 10.1039/C4CP02255F

"Regiodivergent Kinetic Resolution of Terminal and Internal rac-Aziridines with Malonates under Dinuclear Schiff Base Catalysis"

Xu, Y.; Kaneko, K.; Kanai, M.; Shibasaki, M.; Matsunaga, S.
J. Am. Chem. Soc. 2014, 136, 9190. DOI: 10.1021/ja5039165

"Rational Design and Identification of Non-Peptidic Aggregation Inhibitor of Amyloid-β Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-]"

Arai, T.; Araya, T.; Sasaki, D.; Taniguchi, A.; Sato, T.; Sohma, Y.; Kanai, M.
Angew. Chem. Int. Ed. 2014, 53, 8236. DOI: 10.1002/anie.201405109

*Selected as "Hot Paper"

"Serine-Selective Aerobic Cleavage of Peptides and a Protein Using a Water-Soluble Copper-Organoradical Conjugate"

Seki, Y.; Tanabe, K.; Sasaki, D.; Sohma, Y.; Oisaki, K.; Kanai, M.
Angew. Chem. Int. Ed. 2014, 53, 6501. DOI: 10.1002/anie.201402618

*Highligted by Chem-Station Int. Ed.

"Copper-Catalyzed Regio- and Stereoselective Intermolecular Three-Component Oxyarylation of Allenes"

Itoh, T.; Shimizu, Y.; Kanai, M.
Org. Lett. 2014, 16, 2736. DOI: 10.1021/ol501022d

*Featured in SYNFACTS.

"Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C?H Alkenylation/Annulation Sequence"

Ikemoto, H.; Yoshino, T.; Sakata, K.; Matsunaga, S.; Kanai, M.
J. Am. Chem. Soc. 2014, 136, 5424. DOI: 10.1021/ja5008432

* Featured by SJN News.

"Air-Stable Carbonyl(pentamethylcyclopentadienyl)cobalt Diiodide Complex as a Precursor for Cationic (Pentamethylcyclopentadienyl)cobalt(III) Catalysis: Application for Directed C-2 Selective C-H Amidation of Indoles"

Sun, B.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Adv. Synth. Catal. 2014, 356, 1491. DOI: 10.1002/adsc.201301110

*Selected as Cover Picture.

"Palladium-Catalyzed Direct C-H Silylation and Germanylation of Benzamides and Carboxamides"

Kanyiva, K. S.; Kuninobu, Y.; Kanai, M.
Org. Lett. 2014, 16, 1968. DOI: 10.1021/ol500519y

"Regioselective Trifluoromethylation of N-Heteroaromatic Compounds Using Trifluoromethyldifluoroborane Activator"

Nishida, T.; Ida, H.; Kuninobu, Y.; Kanai, M.
Nat. Commun. 2014, 5, 3387. DOI: 10.1038/ncomms4387

*Selected by Nat.Commun. Chemistry Selections.

"Asparagine-Selective Cleavage of Peptide Bonds through Hypervalent Iodine-Mediated Hofmann Rearrangement in Neutral Aqueous Solution"

Tanabe, K.; Taniguchi, A.; Matsumoto, T.; Oisaki, K.; Sohma, Y.; Kanai, M.
Chem. Sci. 2014, 5, 2747. DOI: 10.1039/C3SC53037J

* Most downloaded article (2014/March) of Chem. Sci.

"Copper-Catalyzed Intramolecular C(sp3)-H and C(sp2)-H Amidation by Oxidative Cyclization"

Wang, Z.; Ni, J.; Kuninobu, Y.; Kanai, M.
Angew. Chem. Int. Ed.. 2014, 53, 3496. DOI: 10.1002/anie.201311105

"Copper-Catalyzed Benzylic C(sp3)-H Alkoxylation of Heterocyclic Compounds"

Takemura, N.; Kuninobu, Y.; Kanai, M.
Org. Biomol. Chem. 2014, 12, 2528. DOI: 10.1039/C4OB00215F

"Palladium-Catalyzed C-H Fluorosilylation of 2-Phenylpyridines: Synthesis of Silafluorene Equivalents"

Xiao, Q.; Meng, X.; Kanai, M.; Kuninobu, Y.
Angew. Chem. Int. Ed. 2014, 53, 3168. DOI: 10.1002/anie.201310293

"Synthesis of Pyridine N-Oxide-BF2CF3 Complexes and Their Fluorescence Properties"

Nishida, T.; Fukazawa, A.; Yamaguchi, E.; Oshima, H.; Yamaguchi, S.; Kanai, M.; Kuninobu, Y.
Chem. Asian J. 2014, 9,1026. DOI: 10.1002/asia.201301688

"Cobalt-Catalyzed C-4 Selective Alkylation of Quinolines"

Yamamoto, S.; Saga, Y.; Andou, T.; Matsunaga, S.; Kanai, M.
Adv. Synth. Cat. 2014, 356, 401. DOI: 10.1002/adsc.201300991

"Catalytic enantioselective synthesis of 2-(2-hydroxyethyl)indole scaffolds via consecutive intramolecular amido-cupration of allenes and asymmetric addition of carbonyl compounds"

Chikkade, P. K.; Shimizu, Y.; Kanai, M.
Chem. Sci. 2014, 5, 1585. DOI: 10.1039/C3SC52803K

"A Catalytic C-C Bond-Formation with Minimal Use of Protecting Groups: Construction of Functionalized Isotetronic Acid Derivatives"

Shimizu, Y.; Yasuda, K.; Kanai, M.
Heterocycles 2014, 88, 919. DOI: 10.3987/COM-13-S(S)81

"Enantioselective Synthesis of Spirooxindoles via Direct Catalytic Asymmetric Aldol-Type Reaction of Isothiocyanato Oxindoles"

Kato, S.; Kanai, M.; Matsunaga, S.
Heterocycles 2014, 88, 475. DOI: 10.3987/COM-13-S(S)60

"Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation"

Taniguchi, A.; Sasaki, D.; Shiohara, A.; Iwatsubo, T.; Tomita, T.; Sohma, Y. Kanai, M.
Angew. Chem. Int. Ed. 2014, 53, 1382. DOI: 10.1002/anie.201308001

* Selected as "Hot Paper".
* Featured by JSTプレスリリースマイナビニュースQLifePro、日経産業新聞12月12日付、知るNAVIYahooニュースOPTRONICS


Account & Review (2014)

"Medicinal chemistry focusing on aggregation of amyloid-β peptide"

Sohma, Y.; Taniguchi, A.; Kanai, M.
Kagaku Kogyo 2014, 65, 837.

"Chemoselective aerobic oxidation catalyzed by a metal/stable organoradical redox conjugate"

Seki, Y.; Oisaki, K.; Kanai, M.
Tetrahedron Lett. 2014, 55, 3738. doi:10.1016/j.tetlet.2014.05.085

"Recent progress in copper-catalyzed difunctionalization of unactivated carbon-carbon multiple bonds"

Shimizu, Y.; Kanai, M.
Tetrahedron Lett. 2014, 55, 3727. doi:10.1016/j.tetlet.2014.05.077


生長 幸之助、園部 敏亮、金井 求
和光純薬時報 2014, 82, 2. [PDF]


生長 幸之助
有機合成化学協会誌 2014, 72, 74. doi:10.5059/yukigoseikyokaishi.72.74

"Recent advances in cooperative bimetallic asymmetric catalysis: dinuclear Schiff base complexes"

Matsunaga, S.; Shibasaki, M.
Chem. Commun. 2014, 50, 1044. DOI: 10.1039/C3CC47587E

Patent (2014)

"Aβ peptide oxidant, and use thereof"

Kanai, M.; Sohma, Y.; Taniguchi, A.; Sasaki, D.
PCT Int. Appl. (2014) WO 2014200091 A1 20141218.

"Nitrogenated aromatic compound-N-oxide-borane complexes and fluorescent agents containing them"

Kuninobu, Y.; Kanai, M.; Nishida, T.
PCT Int. Appl. (2014) WO 2014132704 A1 20140904.

"Biotin alterant, streptavidin mutants, and uses thereof"

Sugiyama, A.; Doi, H.; Kodama, T.; Inoue, T.; Mizohata, E.; Kawato, T.; Meshizuka, T.; Kanai, M.; Shimizu, Y.; Yamamoto, T.
PCT Int. Appl. (2014) WO 2014129446 A1 20140828.

"Cyclic peptide and pharmaceutical product containing same for inhibition of amyloid β aggregation"

Kanai, M.; Sohma, Y.; Arai, T.; Sasaki, D.; Kobayashi, Y.
PCT Int. Appl. (2014) WO 2014103481 A1 20140703.

"Fluorescent imaging reagent for acetylation in cells and visualization of intracellular acetylation using the reagent"

Kanai, M.; Komatsu, H.
PCT Int. Appl. (2014) WO 2014057999 A1 20140417.



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