Publication List (2015)
"Catalytic Asymmetric Iterative/Domino Aldehyde Cross-Aldol Reactions for the Rapid and Flexible Synthesis of 1,3-Polyols"
Lin, L.; Yamamoto, K.; Mitsunuma, H.; Kanzaki, Y.; Matsunaga, S.; Kanai,
M.
J. Am. Chem. Soc. 2015, 137, 15418.
DOI: 10.1021/jacs.5b11192
*Featured by UT press release.
"Supramolecular Ligands for Histone Tails by Employing a Multivalent Display of Trisulfonated Calix[4]arenes"
Kimura, Y.; Saito, N.; Hanada, K.; Liu, J.; Okabe, T.; Kawashima, S.
A.; Yamatsugu, K.; Kanai, M.
ChemBioChem 2015, 16, 2599.
DOI: 10.1002/cbic.201500448
"Cp*CoIII Catalyzed Site-Selective C-H Activation of Unsymmetrical O-Acyl Oximes: Synthesis of Multisubstituted Isoquinolines from Terminal and Internal Alkynes"
Sun, B.; Yoshino, T.; Kanai, M.; Matsunaga, S.
Angew. Chem. Int. Ed. 2015, 54，12968.
DOI: 10.1002/anie.201507744
"Copper-Catalyzed Oxyboration of Unactivated Alkenes"
Itoh, T.; Matsueda, T.; Shimizu, Y.; Kanai, M.
Chem. Eur. J. 2015, 21, 15955. DOI:
10.1002/chem.201503329
"A meta-selective C-H borylation directed by a secondary interaction between ligand and substrate"
Kuninobu, Y.; Ida, H.; Nishi, M.; Kanai, M.
Nat. Chem. 2015, 7, 712.
DOI: 10.1038/nchem.2322
* Highlighted by JST press release(Japanese, English), Nat. Chem. News & Views, 東大薬学部ニュース, 化学工業日報, 日経バイオテック, Chem-Station (Japanese, Chinese)、薬事日報.
"Benzylic C(sp3)-H Perfluoroalkylation of Six-Membered Heteroaromatic Compounds"
Kuninobu, Y.; Nagase, M.; Kanai, M.
Angew. Chem. Int. Ed. 2015, 54, 10263.
DOI: 10.1002/anie.201505335
"Dehydrative Direct C-H Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis"
Suzuki, Y.; Sun, B.; Sakata, K.; Yoshino, T.; Matsunaga, S.; Kanai,
M.
Angew. Chem. Int. Ed. 2015, 54, 9944.
DOI: 10.1002/anie.201503704
*Featured by JSTプレスリリース, マイナビニュース, 薬事日報
"Organocatalytic Aerobic Oxdation to α-Fluoroalkyl Alcohols to Fluoroalkyl Ketones at Room Temperature"
Kadoh, Y.; Tashiro, M.; Oisaki, K.; Kanai, M.
Adv. Synth. Catal. 2015, 357, 2193.
DOI: 10.1002/adsc.201500131
"Chemoselective Boron-Catalyzed Nucleophilic Activation of Carbox-
ylic Acids for Mannich-Type Reactions"
Morita, Y.; Yamamoto, T.; Nagai, H.; Shimizu, Y.; Kanai, M.
J. Am. Chem. Soc. 2015, 137, 7075.
DOI: 10.1021/jacs.5b04175
* Highlighted by UTokyo Research
(Japanese)
(English), Department
News, Chem-Station,
Synform
.
"Synthesis of chemically-tethered amyloid-β segment trimer possessing amyloidogenic properties"
Shinoda, K.; Sohma, Y.; Kanai, M.
Bioorg. Med. Chem. Lett. 2015, 25,
2976. doi:10.1016/j.bmcl.2015.05.029
"Covalent modifier-type aggregation inhibitor of amyloid-β based on a cyclo-KLVFF motif"
Kino, R.; Araya, T.; Arai, T.; Sohma, Y.; Kanai, M.
Bioorg. Med. Chem. Lett. 2015, 25,
2972. doi:10.1016/j.bmcl.2015.05.027
"Metal-free C(3)-H arylation of coumarins promoted by catalytic amounts of 5,10,15,20-tetrakis(4-diethylaminophenyl)porphyrin"
Kojima, M.; Oisaki, K.; Kanai, M.
Chem. Commun. 2015, 51, 9718. DOI:
10.1039/C5CC02349A
"Palladium-Catalyzed Oxirane-Opening Reaction with Arenes via C-H Bond Activation"
Wang, Z.; Kuninobu, Y.; Kanai, M.
J. Am. Chem. Soc. 2015, 137, 6140.
DOI: 10.1021/jacs.5b02435
"Palladium-Catalyzed Construction of Heteroatom-Containing π-Conjugated Systems by Intramolecular Oxidative C-H/C-H Coupling Reaction"
Saito, K.; Chikkade, P. K.; Kanai, M.; Kuninobu, Y.
Chem. Eur. J. 2015, 21, 8365.
DOI: 10.1002/chem.201501116
"Rhodium-Catalysed Synthesis of Multi-Substituted Silylindenes from Aryl Alkynes and Hydrosilanes via C-H Bond Activation"
Sueki, S.; Kuninobu, Y.
Chem. Commun. 2015, 51, 7685. doi:10.1039/C5CC01569C
"Copper-Catalyzed Intermolecular C(sp3)-H Bond Functionalization Towards the Synthesis of Tertiary Carbamates"
Chikkade, P. K.; Kuninobu, Y.; Kanai, M.
Chem. Sci. 2015, 6, 3195.
doi: 10.1039/C5SC00238A
"Iridium-Catalyzed ortho-Selective C-H Silylation of Aromatic Compounds Directed toward the Synthesis of π-Conjugated Molecules with Lewis Acid-Base Interaction"
Wakaki, T.; Kanai, M.; Kuninobu, Y.
Org. Lett. 2015, 17, 1758.
doi:10.1021/acs.orglett.5b00529
"Cp*Co(III)-catalyzed oxidative C-H alkenylation of benzamides with ethyl acrylate"
Suzuki, Y.; Sun, B.; Yoshino, T.; Kanai, M.; Matsunaga, S.
Tetrahedron 2015, 71, 4552.
doi:10.1016/j.tet.2015.02.032
"Structure-based design of a streptavidin mutant specific for an artificial biotin analogue"
Kawato, T.; Mizohata, E.; Shimizu, Y.; Mshizuka, T.; Yamamoto, T.;
Takasu, N.; Matsuoka, M.; Matsumura, H.; Kodama, T.; Kanai, M.; Doi,
H.; Inoue, T.; Sugiyama, A.
J. Biochem. 2015, 157, 457.
DOI: 10.1093/jb/mvv004
"Design and synthesis of biotin analogues reversibly binding with streptavidin"
Yamamoto, T.; Aoki, K.; Sugiyama, A.; Doi, H.; Kodama, T.; Shimizu,
Y.; Kanai, M.
Chem. Asian J. 2015, 10, 1071. DOI:
10.1002/asia.201500120
"A Cp*CoI2-dimer as a precursor for cationic Co(III)-catalysis: application to C-H phosphoramidation of indoles"
Sun, B.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Chem. Commun. 2015, 51, 4649. DOI:
10.1039/C4CC10284C
"Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant"
Kawato, T.; Mizohata, E.; Shimizu, Y.; Meshizuka, Y.; Yamamoto, T.;
Takasu, N.; Matsuoka, M.; Matsumura, H.; Kodama, T.; Kanai, M.; Doi,
H.; Inoue, T.; Sugiyama, A.
Bioscience, Biotechnology, and Biochemistry 2015,
79, 640. DOI: 10.1080/09168451.2014.991692
Account & Review （2015）
Patent （2015）
"Artificial catalyst system capable of substituting for in vivo acylation function"
Kanai, M.; Kawashima, S.; Yamatsugu, K.; Zhu, H.; Amamoto, Y.; Tanabe,
K.; Ishiguro, T.; Liu, J.
PCT Int. Appl. (2015) WO 2015186785 A1 20151210.
"System for sequential controlled release of functional molecule"
Kanai, M.; Soma, Y.; Tanabe, K.
PCT Int. Appl. (2015) WO 2015137064 A1 20150917.
"Biotin variant dimer, streptavidin mutant, and uses thereof"
Sugiyama, A.; Doi, H.; Kodama, T.; Inoue, T.; Mizohata, E.; Kawato,
T.; Meshizuka, T.; Kanai, M.; Shimizu, Y.; Takasu, N. et al.
PCT Int. Appl. (2015) WO 2015125820 A1 20150827.
"Preparation of bipyridyl compounds having benzeneureido skeletons, and regioselective aromatic borylation catalysts using them"
Kuninobu, Y.; Kanai, M.; Ida, H.; Nishi, M.
PCT Int. Appl. (2015) WO 2015115519 A1 20150806.
"Preparation of amide compounds and their salts, β-amyloid aggregation inhibitors, and preventive and therapeutic method of Alzheimer disease"
Kanai, M.; Soma, Y.; Arai, T.; Araya, T.
PCT Int. Appl. (2015) WO 2015087865 A1 20150618.
