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2017

  1. Ohigashi I, Ohte Y, Setoh K, Nakase H, Maekawa A, Kiyonari H, Hamazaki Y, Sekai M, Sudo T, Tabara Y, Sawai H, Omae Y, Yuliwulandari R, Tanaka Y, Mizokami M, Inoue H, Kasahara M, Minato N, Tokunaga K, Tanaka K, Matsuda F, Murata S, Takahama Y. A human PSMB11 variant affects thymoproteasome processing and CD8+ T cell production. JCI Insight. 2017 May 18;2(10). pii: 93664. doi: 10.1172/jci.insight.93664. [Epub ahead of print] [abstract]
  2. Jiang RT, Yemelyanova A, Xing D, Anchoori RK, Hamazaki J, Murata S, Seidman JD, Wang TL, Roden RBS. Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma. J Ovarian Res. 2017 Aug 7;10(1):53. doi: 10.1186/s13048-017-0347-y. [abstract]
  3. Lu X, Nowicka U, Sridharan V, Liu F, Randles L, Hymel D, Dyba M, Tarasov SG, Tarasova NI, Zhao XZ, Hamazaki J, Murata S, Burke TR Jr, Walters KJ. Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets. Nat Commun. 2017 Jun 9;8:15540. doi: 10.1038/ncomms15540. [abstract]
  4. Nitta T, Kochi Y, Muro R, Tomofuji Y, Okamura T, Murata S, Suzuki H, Sumida T, Yamamoto K, Takayanagi H. Human thymoproteasome variations influence CD8 T cell selection. Sci Immunol. 2017 Jun 2;2(12). pii: eaan5165. doi: 10.1126/sciimmunol.aan5165. Epub 2017 Jun 2. [abstract]
  5. Uddin MM, Ohigashi I, Motosugi R, Nakayama T, Sakata M, Hamazaki J, Nishito Y, Rode I, Tanaka K, Takemoto T, Murata S, Takahama Y. Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus. Nat Commun. 2017 Feb 8;8:14419. doi: 10.1038/ncomms14419.[abstract]

2016

  1. Kincaid EZ, Murata S, Tanaka K, Rock KL. Specialized proteasome subunits have an essential role in the thymic selection of CD8(+) T cells. Nat Immunol. 2016 Aug;17(8):938-45. doi: 10.1038/ni.3480. Epub 2016 Jun 13. [abstract]
  2. Koizumi S, Irie T, Hirayama S, Sakurai Y, Yashiroda H, Naguro I, Ichijo H, Hamazaki J, Murata S. The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction. Elife. 2016 Aug 16;5. pii: e18357. doi: 10.7554/eLife.18357.[abstract]

2015

  1. Jeeyeon Cha, Kristin E Burnum-Johnson, Amanda Bartos, Yingju Li, Erin S Baker, Susan C Tilton, Bobbie-Jo M Webb-Robertson, Paul D Piehowski, Matthew E Monroe, Anil G Jegga, Shigeo Murata, Yasushi Hirota, Sudhansu K Dey. Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus. Journal of Biological Chemistry 04/2015; 290(24). DOI:10.1074/jbc.M115.655001. [abstract]
  2. Jun Hamazaki, Shoshiro Hirayama, Shigeo Murata. Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genetics 07/2015; 11(7):e1005401. DOI:10.1371/journal.pgen.1005401, 8.17.[abstract]
  3. Katsuhiro Sasaki, Kensuke Takada, Yuki Ohte, Hiroyuki Kondo, Hiroyuki Sorimachi, Keiji Tanaka, Yousuke Takahama, Shigeo Murata. Thymoproteasomes produce unique peptide motifs for positive selection of CD8+ T cells. Nature Communications 06/2015; 6:7484. DOI:10.1038/ncomms8484, 10.74.[abstract]
  4. Kensuke Takada, Francois Van Laethem, Yan Xing, Kazuyuki Akane, Haruhiko Suzuki, Shigeo Murata, Keiji Tanaka, Stephen C Jameson, Alfred Singer, Yousuke Takahama. Impact Factor. TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells. Nature Immunology 08/2015; DOI:10.1038/ni.3237, 24.97. [abstract]
  5. K Morita, Y Masamoto, K Kataoka, J Koya, Y Kagoya, H Yashiroda, T Sato, S Murata, M Kurokawa. BAALC potentiates oncogenic ERK pathway through interactions with MEKK1 and KLF4. Leukemia: official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 06/2015; DOI:10.1038/leu.2015.137, 9.38. [abstract]
  6. yohei Shirozu, Hideki Yashiroda, Shigeo Murata. Identification of minimum Rpn4-responsive elements in genes related to proteasome functions. FEBS Letters 03/2015; 67(8). DOI:10.1016/j.febslet.2015.02.025, 3.34. [abstract]
  7. Takeshi Nitta, Ryunosuke Muro, Yukiko Shimizu, Sachiko Nitta, Hiroyo Oda, Yuki Ohte, Motohito Goto, Rieko Yanobu‐Takanashi, Tomoya Narita, Hiroshi Takayanagi, Hisataka Yasuda, Tadashi Okamura, Shigeo Murata, Harumi Suzuki. The thymic cortical epithelium determines the TCR repertoire of IL-17-producing T cells., EMBO Reports 03/2015; 16(5). DOI:10.15252/embr.201540096, 7.86. [abstract]
  8. Takuya Tomita, Jun Hamazaki, Shoshiro Hirayama, Michael W McBurney, Hideki Yashiroda, Shigeo Murata. Sirt1-deficiency causes defective protein quality control. Scientific Reports 07/2015; 5:12613. DOI:10.1038/srep12613, 5.58. [abstract]

2014

  1. Hideki Yashiroda, Yousuke Toda, Saori Otsu, Kenji Takagi, Tsunehiro Mizushima, Shigeo Murata. N-Terminal α7 Deletion of the Proteasome 20S Core Particle Substitutes for Yeast PI31 Function. Molecular and Cellular Biology 10/2014; 35(1). DOI:10.1128/MCB.00582- 14 · 5.04. [abstract]
  2. Kenji Takagi, Yasushi Saeki, Hideki Yashiroda, Hirokazu Yagi, Ai Kaiho, Shigeo Murata, Takashi Yamane, Keiji Tanaka, Tsunehiro Mizushima, Koichi Kato. Pba3–Pba4 heterodimer acts as a molecular matchmaker in proteasome α-ring formation. Biochemical and Biophysical Research Communications 07/2014; 450(2). DOI:10.1016/j.bbrc.2014.06.119 · 2.28. [abstract]
  3. Minghui Bai, Xian Zhao, Kazutaka Sahara, Yuki Ohte, Yuko Hirano, Takeumi Kaneko, Hideki Yashiroda, Shigeo Murata. Assembly Mechanisms of Specialized Core Particles of the Proteasome. 09/2014; 4(3):662-677. DOI:10.3390/biom4030662. [abstract]
  4. Pack CG, Yukii H, Toh-e A, Kudo T, Tsuchiya H, Kaiho A, Sakata E, Murata S, Yokosawa H, Sako Y, Baumeister W, Tanaka K, Saeki Y. Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome. Nat Commun. 2014 Mar 6;5:3396.[abstract]
  5. Sahara K, Kogleck L, Yashiroda H, Murata S. The mechanism for molecular assembly of the proteasome. Adv Biol Regul. 2014 Jan;54:51-8.[abstract]
  6. Uechi H, Hamazaki J, Murata S. Characterization of the testis-specific proteasome subunit α4s in mammals. J Biol Chem. 2014 May 2;289(18):12365-74.[abstract]

2013

  1. Akahane, T., Sahara, K., Yashiroda, H., Tanaka, K., and Murata, S. Involvement of Bag6 and the TRC pathway in proteasome assembly. Nat Commun. 4:2234, 2013. [abstract]
  2. Iwai C, Li P, Kurata Y, Hoshikawa Y, Morikawa K, Maharani N, Higaki K, Sasano T, Notsu T, Ishido Y, Miake, J, Yamamoto Y, Shirayoshi Y, Ninomiya H, Nakai A, Murata S, Yoshida A, Yamamoto K, Hiraoka M, Hisatome I.. Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins. Cardiovasc Res. 2013 Sep 17.[abstract]
  3. Odaka C., Loranger A, Takizawa K, Ouellet M, Tremblay MJ, Murata S, Inoko A, Inagaki M, Marceau N. Keratin 8 is required for the maintenance of architectural structure in thymus epithelium. PLoS One 8(9):e75101, 2013.[abstract]
  4. Ohigashi I, Zuklys S, Sakata M, Mayer CE, Zhanybekova S, Murata S, Tanaka K, Holländer GA, Takahama Y.: Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9885-90 [abstract]
  5. Otoda T, Takamura T, Misu H, Ota T, Murata S, Hayashi H, Takayama H, Kikuchi A, Kanamori T, Shima KR, Lan F, Takeda T, Kurita S, Ishikura K, Kita Y, Iwayama K, Kato K, Uno M, Takeshita Y, Yamamoto M, Tokuyama K, Iseki S, Tanaka K, Kaneko S.: Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver. Diabetes. 2013 Mar;62(3):811-24. [abstract]
  6. Sahara K, Kogleck L, Yashiroda H, Murata S. The mechanism for molecular assembly of the proteasome. Adv Biol Regul. S2212-4926 (13) 00084-5, 2013. [abstract]
  7. Sasaki Y, Sano S, Nakahara M, Murata S, Kometani K, Aiba Y, Sakamoto S, Watanabe Y, Tanaka K, Kurosaki T, Iwai K. Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells. EMBO J. 32(18):2463-76, 2013. [abstract]
  8. Seung-Wook Shin, Shigeo Murata, Kazuya Matsumoto. The Ubiquitin-Proteasome System in the Maternal-to-Zygotic Transitionl., Journal of Mammalian Ova Research 10/2013; 30(3):79-85. DOI:10.1274/jmor.30.79. [abstract]
  9. Shin SW, Shimizu N, Tokoro M, Nishikawa S, Hatanaka Y, Anzai M, Hamazaki J, Kishigami S, Saeki K, Hosoi Y, Iritani A, Murata S, Matsumoto K.: Mouse zygote-specific proteasome assembly chaperone important for maternal-to-zygotic transition. Biol Open. 2013 Feb 15;2(2):170-82. [abstract]

2012

  1. Chou B, Hiromatsu K, Okano S, Ishii K, Duan X, Sakai T, Murata S, Tanaka K, Himeno K.: Antiangiogenic Tumor Therapy by DNA Vaccine Inducing Aquaporin-1-Specific CTL Based on Ubiquitin-Proteasome System in Mice. J Immunol. 2012 [abstract]
  2. Kaneko T, Murata S.: Using siRNA techniques to dissect proteasome assembly pathways in mammalian cells. Methods Mol Biol. 2012; 832: 433-42 [abstract]
  3. Nakagawa Y, Ohigashi I, Nitta T, Sakata M, Tanaka K, Murata S, Kanagawa O, Takahama Y. Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes. Proc Natl Acad Sci U S A. 109(50):20572-7, 2012. [abstract]
  4. Takahama Y, Takada K, Murata S, Tanaka K.: β5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells. Curr Opin Immunol. 2012 24 (1): 92-8 [abstract]
  5. Tomaru U, Takahashi S, Ishizu A, Miyatake Y, Gohda A, Suzuki S, Ono A, Ohara J, Baba T, Murata S, Tanaka K, Kasahara M.: Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities. Am J Pathol. 2012 180 (3): 963-72. [abstract]

2011

  1. Kitamura A, Maekawa Y, Uehara H, Izumi K, Kawachi I, Nishizawa M, Toyoshima Y, Takahashi H, Standley DM, Tanaka K, Hamazaki J, Murata S, Obara K, Toyoshima I, Yasutomo K.: A mutation in an immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans, J Clin Invest. 2011 121 (10): 4150-60. [abstract]
  2. Arima K, Kinoshita A, Mishima H, Kanazawa N, Kaneko T, Mizushima T, Ichinose K, Nakamura H, Tsujino A, Kawakami A, Matsunaka M, Kasagi S, Kawano S, Kumagai S, Ohmura K, Mimori T, Hirano M, Ueno S, Tanaka K, Tanaka M, Toyoshima I, Sugino H, Yamakawa A, Tanaka K, Niikawa N, Furukawa F, Murata S, Eguchi K, Ida H, Yoshiura KI.: Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome., Proc Natl Acad Sci U S A. 2011 Aug 18. [Epub ahead of print] [abstract]
  3. Ripen AM, Nitta T, Murata S, Tanaka K, Takahama Y.: Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t., Eur J Immunol. 2011 May;41(4):1278-87 [abstract]
  4. Oh KH, Yang SW, Park JM, Seol JH, Iemura S, Natsume T, Murata S, Tanaka K, Jeon YJ, Chung CH.: Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme., Cell Death Differ. 2011 Aug;18(8):1326-36. [abstract]

2010

  1. Chou B, Hiromatsu K, Hisaeda H, Duan X, Imai T, Murata S, Tanaka K, Himeno K.: Genetic immunization based on the ubiquitin-fusion degradation pathway against Trypanosoma cruzi., Biochem Biophys Res Commun. 2010 Feb 12;392(3):277-82. Epub 2010 Jan 7. [abstract]
  2. Duan X, Hisaeda H, Shen J, Tu L, Imai T, Chou B, Murata S, Chiba T, Tanaka K, Fehling HJ, Koga T, Sueishi, K., and Himeno, K. (2006): The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells., Int Immunol 18, 679-687. [abstract]
  3. Florea BI, Verdoes M, Li N, van der Linden WA, Geurink PP, van den Elst H, Hofmann T, de Ru A, van Veelen PA, Tanaka K, Sasaki K, Murata S, den Dulk H, Brouwer J, Ossendorp FA, Kisselev AF, Overkleeft HS.: Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t., Chem Biol. 2010 Aug 27;17(8):795-801[abstract]
  4. Maruyama T, Kadowaki H, Okamoto N, Nagai A, Naguro I, Matsuzawa A, Shibuya H, Tanaka K, Murata S, Takeda K, Nishitoh H, Ichijo H.: CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response., EMBO J. 2010 Aug 4;29(15):2501-14. [abstract]
  5. Nitta T, Murata S, Sasaki K, Fujii H, Ripen AM, Ishimaru N, Koyasu S, Tanaka K, Takahama Y.: Thymoproteasome Shapes Immunocompetent Repertoire of CD8(+) T Cells., Immunity. 2010 Jan 29;32(1):29-40. Epub 2009 Dec31. 23-32 [abstract]
  6. Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S.: PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis., Mol Cell Biol. 2010 Aug;30(15):3864-74. Epub 2010 May 24. [abstract]
  7. Takahama Y, Nitta T, Mat Ripen A, Nitta S, Murata S, Tanaka K.: Role of thymic cortex-specific self-peptides in positive selection of T cells., Semin Immunol. 2010 Oct;22(5):287-93. [abstract]

2009

  1. Hendil KB, Kriegenburg F, Tanaka K, Murata S, Lauridsen AM, Johnsen AH, Hartmann-Petersen R.: The 20S proteasome as an assembly platform for the 19S regulatory complex., J Mol Biol. 394 (2): 320-8 [abstract]
  2. Kaneko T, Hamazaki J, Iemura S, Sasaki K, Furuyama K, Natsume T, Tanaka K, Murata S.: Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones., Cell. 137 (5): 914-25 [abstract]
  3. Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K.: An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis., Cell. 137 (3): 549-59 [abstract]
  4. Murata S, Yashiroda H, Tanaka K.: Molecular mechanisms of proteasome assembly., Nat Rev Mol Cell Biol. 10(2): 104-15 [abstract]
  5. Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J, Murata S, Tanaka K, Morimoto Y.: Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain., Biochem Biophys Res Commun. 390 (3): 855-60[abstract]
  6. Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.. 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse. Hum Mol Genet. 18(5):898-910, 2009. [abstract]
  7. Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, Akira S, Takao T, Tanaka K, Iwai K.: Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation., Nat Cell Biol. 11 (2): 123-32 [abstract]
  8. Tomaru U, Ishizu A, Murata S, Miyatake Y, Suzuki S, Takahashi S, Kazamaki T, Ohara J, Baba T, Iwasaki S, Fugo K, Otsuka N, Tanaka K, Kasahara M.: Exclusive expression of proteasome subunit beta 5t in the human thymic cortex., Blood. 113 (21): 5186-91 [abstract]
  9. Tonoki A, Kuranaga E, Tomioka T, Hamazaki J, Murata S, Tanaka K, Miura M.: Genetic evidence linking age-dependent attenuation of the 26S proteasome with aging process., Mol Cell Biol. 2009 29 (4): 1095-106. [abstract]
  10. Tu L, Moriya C, Imai T, Ishida H, Tetsutani K, Duan X, Murata S, Tanaka K, Shimokawa C, Hisaeda H, Himeno K.: Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection., Eur J Immunol. 39 (12): 3385-94 [abstract]

2008

  1. Chou B, Hisaeda H, Shen J, Duan X, Imai T, Tu L, Murata S, Tanaka K, Himeno K.  Critical contribution of immunoproteasomes in the induction of protective immunity against Trypanosoma cruzi in mice vaccinated with a plasmid encoding a CTL epitope fused to green fluorescence protein., Microbes Infect. 10: 241-50 (2008) [abstract]
  2. Hirano, Y., Kaneko, T., Okamoto, K., Bai, M., Yashiroda, H., Furuyama, K., Kato, K., Tanaka, K., Murata, S.: Dissecting beta-ring assembly pathway of the mammalian 20S proteasome. EMBO J. 27: 2204-2213 (2008) [abstract]
  3. Murata S, Takahama Y, Tanaka K. Thymoproteasome: probable role in generating positively selecting peptides., Curr Opin Immunol. 20: 192-196 (2008) [abstract]
  4. Nitta T, Murata S, Ueno T, Tanaka K, Takahama Y.: Thymic microenvironments for T-cell repertoire formation., Adv Immunol. 99:59-94 [abstract]
  5. Takahama Y, Tanaka K, Murata S. Modest cortex and promiscuous medulla for thymic repertoire formation., Trends Immunol. 29: 251-255 (2008) [abstract]
  6. Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G. 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse., Hum Mol Genet. 2008 Dec 9 [Epub ahead of print]. [abstract]
  7. Yamano T, Mizukami S, Murata S, Chiba T, Tanaka K, Udono H. Hsp90-mediated assembly of the 26 S proteasome is involved in major histocompatibility complex class I antigen processing., J Biol Chem. 283(42):28060-5. [abstract]
  8. Yamano T, Sugahara H, Mizukami S, Murata S, Chiba T, Tanaka K, Yui K, Udono H. Allele-selective effect of PA28 in MHC class I antigen processing., J. Immunol. 181(3):1655-64. [abstract]
  9. Yashiroda, H., Mizushima, T., Okamoto, K., Kameyama, T., Hayashi, H., Kishimoto, T., Kasahara , M., Kurimoto, E., Sakata, E., Suzuki, A., Yuko Hirano, Y., Murata , S., Kato, K., Yamane, T., and Tanaka, K. (2008) Crystal Structure of a Chaperone Complex that Contributes to the Assembly of Yeast 20S Proteasomes., Nature Struct. Mol. Biol. 15, 228 − 236 [abstract]

2007

  1. Hamazaki, J., Sasaki, K., Kawahara, H., Hisanaga, S., Tanaka, K. and Murata, S. (2007): Rpn10-mediated degradation of ubiquitinated proteins is essential for mammalian development., Mol Cell Biol 27, 6629-6638. [abstract]
  2. Isono, E., Nishihara, K., Saeki, Y., Yashiroda, H., Kamata, N., Ge, L., Ueda, T., Kikuchi, Y., Tanaka, K., Nakano, A. and Toh-e, A.: The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome., Mol Biol. Cell 18, 569-80 [abstract]
  3. Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K.: Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice., Cell. 131(6):1149-63. [abstract]
  4. Miyamoto, H., Moriishi, K., Moriya, K., Murata, S., Tanaka, K., Suzuki, T., Miyamura, T., Koike, K., and Matsuura, Y. (2007): Involvement of the PA28g-dependent pathway in insulin resistance induced by hepatitis C virus core protein., J Virol 81, 1727-1735 [abstract]
  5. Moriishi, K., Mochizuki, R., Moriya, K., Miyamoto, H., Mori, Y., Abe, T., Murata, S., Tanaka, K., Miyamura, T., Suzuki, T., Koike, K., and Matsuura, Y. (2007): Critical role of PA28g in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis., Proc Natl Acad Sci U S A 104, 1661-1666 [abstract]
  6. Murata, S., Sasaki, K., Kishimoto, T., Hayashi, H., Niwa, S., Takahama, Y., and Tanaka, K. (2007): Regulation of CD8+ T cell development by thymus-specific proteasomes., Science 316, 1349-1353. [abstract]

2006

  1. Duan, X., Hisaeda, H., Shen, J., Tu, L., Imai, T., Chou, B., Murata, S., Chiba, T., Tanaka, K., Fehling, H. J., Koga, T., Sueishi, K., and Himeno, K. (2006): The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells., Int Immunol 18, 679-687. [abstract]
  2. Hamazaki, J., Iemura, SI., Natsume, T., Yashiroda, H., Tanaka, K., and Murata S.(2006): A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasome., EMBO J. 25, 4524-4536. [abstract]
  3. Hirano, Y., Hayashi, H., Iemura, S., Hendil, K. B., Niwa, S., Kishimoto, T., Kasahara, M., Natsume, T., Tanaka, K., and Murata, S. (2006): Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes., Mol Cell 24, 977-984. [abstract]
  4. Ishii, K., Hisaeda, H., Duan, X., Imai, T., Sakai, T., Fehling, H. J., Murata, S., Chiba, T., Tanaka, K., Hamano, S., Sano, M., Yano, A., and Himeno, K. (2006): The involvement of immunoproteasomes in induction of MHC class I-restricted immunity targeting Toxoplasma SAG1., Microbes Infect 8, 1045-1053. [abstract]
  5. Kirisako, T., Kamei, K., Murata, S., Kato, M., Fukumoto, H., Kanie, M., Sano, S., Tokunaga, F., Tanaka, K., and Iwai, K. (2006): A ubiquitin ligase complex assembles linear polyubiquitin chains., EMBO J 25, 4877-4887. [abstract]
  6. Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J., Tanida, I., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., and Tanaka, K. (2006): Loss of autophagy in the central nervous system causes neurodegeneration in mice., Nature 441, 880-884. [abstract]
  7. Murata, S. (2006): Multiple chaperone-assisted formation of mammalian 20S proteasomes., IUBMB Life 58, 344-348 [abstract]

2005

  1. Hirano, Y., Hendil, K. B., Yashiroda, H., Iemura, S., Nagane, R., Hioki, Y., Natsume, T., Tanaka, K. and *Murata, S.: A novel heterodimeric complex that promotes the assembly of mammalian 20S proteasomes. Nature., 437, 1381-1385, 2005.
  2. Hirano, Y., Murata, S., and Tanaka, K. (2005): Large- and Small-Scale Purification of Mammalian 26S Proteasomes. Methods Enzymol 399, 227-240.
  3. Jana, N. R., Dikshit, P., Goswami, A., Kotliarova, S., Murata, S., Tanaka, K., and *Nukina, N. (2005): Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes., J Biol Chem 280, 11635-11640.
  4. Komatsu, M., Waguri, S., Ueno, T., Iwata, J., Murata, S., Tanida, I., Ezaki, J., Mizushima, N., Ohsumi, Y., Uchiyama, Y., Kominami, E., Tanaka, K., and *Chiba, T. (2005): Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice., J Cell Biol 169, 425-434.
  5. Murata, S., Minami, M., and Minami, Y. (2005): Purification and assay of the chaperone-dependent ubiquitin ligase of the carboxyl terminus of Hsc70-interacting protein., Methods Enzymol 398, 271-279
  6. Sahara, N., Murayama, M., Mizoroki, T., Urushitani, M., Imai, Y., Takahashi, R., Murata, S., Tanaka, K., and Takashima, A. (2005): In vivo evidence of CHIP up-regulation attenuating tau aggregation.,J Neurochem 94, 1254-1263.
  7. Tanaka, K., Yashiroda, H. and Tanahashi, N.: Preparation of proteasomes. “Cell Biology: A Laboratory Handbook” (Ed. By J. E. Celis) 3rd edition., Academic Press New York. 91-97, 2005.
  8. Zhang, M., Obata, C., Hisaeda, H., Ishii, K., Murata, S., Chiba, T., Tanaka, K., Li, Y., Furue, M., Chou, B., Imai, T., Duan, X., and *Himeno, K. (2005) A novel DNA vaccine based on ubiquitin-proteasome pathway targeting 'self'-antigens expressed in melanoma/melanocyte.: Gene Ther 12, 1049-1057.

2004

  1. Obata, C., Zhang, M., Moroi, Y., Hisaeda, H., Tanaka, K., Murata, S., Furue, M., and Himeno, K. (2004): Formalin-fixed tumor cells effectively induce antitumor immunity both in prophylactic and therapeutic conditions., J Dermatol Sci 34, 209-219.
  2. Tateishi, Y., Kawabe, Y., Chiba, T., Murata, S., Ichikawa, K., Murayama, A., Tanaka, K., Baba, T., Kato, S., and Yanagisawa, J. (2004): Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor., EMBO J 23, 4813-4823.
  3. Tenno, T., Fujiwara, K., Tochio, H., Iwai, K., Morita, E. H., Hayashi, H., Murata, S., Hiroaki, H., Sato, M., Tanaka, K., and *Shirakawa, M. (2004): Structural basis for distinct roles of Lys63- and Lys48-linked polyubiquitin chains., Genes Cells 9, 865-875.
  4. Yashiroda, H. and *Tanaka, K.: Hub1 is an essential ubiquitin-like protein without functioning as a typical modifier in fission yeast., Genes Cells. 9, 1189-1197, 2004.
  5. Zhang, M., Ishii, K., Hisaeda, H., Murata, S., Chiba, T., Tanaka, K., Li, Y., Obata, C., Furue, M., and *Himeno, K. (2004): Ubiquitin-fusion degradation pathway plays an indispensable role in naked DNA vaccination with a chimeric gene encoding a syngeneic cytotoxic T lymphocyte epitope of melanocyte and green fluorescent protein., Immunology 112, 567-574.

2003

  1. Hirano, Y., Murata, S., Tanaka, K., Shimizu, M., and Sato, R. (2003) Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway., J Biol Chem 278, 16809-16819.
  2. Imai, J., Maruya, M., Yashiroda, H., Yahara, I. and Tanaka, K.: The molecular chaperone Hsp90 plays a role in the assesmbly and maintenance of the 26S proteasome., EMBO, J. 22, 3557-3567, 2003
  3. Imai, J., Yashiroda, H., Maruya, M., Yahara, I. and Tanaka, K.: Proteasomes and molecular chaperones: cellular machinery responsible for folding and destruction of unfolded proteins., Cell Cycle 2, 585-590, 2003
  4. Moriishi, K., Okabayashi, T., Nakai, K., Moriya, K., Koike, K., Murata, S., Chiba, T., Tanaka, K., Suzuki, R., Suzuki, T., Miyamura, T., and *Matsuura, Y. (2003): Proteasome activator PA28g-dependent nuclear retention and degradation of hepatitis C virus core protein., J Virol 77, 10237-10249.
  5. Yashiroda, H. and *Tanaka, K.: But1 and But2 proteins bind to Uba3, a catalytic subunit of E1 for neddylation, in fission yeast. Biochem. Biophys. Res. Commun. 311, 691-695, 2003

2002

  1. Kaida D, Yashiroda, H. Toh-e A., Kikuchi Y.: Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression., Genes Cells. 7(6): 543-52 2002.
  2. Niwa, J., Ishigaki, S., Hishikawa, N., Yamamoto, M., Doyu, M., Murata, S., Tanaka, K., Taniguchi, N., and Sobue, G. (2002): Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity., J Biol Chem 277, 36793-36798.
  3. Yamano, T., Murata, S., Shimbara, N., Tanaka, N., Chiba, T., Tanaka, K., Yui, K., and Udono, H. (2002): Two distinct pathways mediated by PA28 and hsp90 in major histocompatibility complex class I antigen processing., J Exp Med 196, 185-196.

2001

  1. Murata, S., Minami, Y., Minami, M., Chiba, T., and Tanaka, K. (2001): CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein., EMBO Rep 2, 1133-1138.
  2. Murata, S., Udono, H., Tanahashi, N., Hamada, N., Watanabe, K., Adachi, K., Yamano, T., Yui, K., Kobayashi, N., Kasahara, M., Tanaka, K., and Chiba, T. (2001): Immunoproteasome assembly and antigen presentation in mice lacking both PA28a and PA28b., EMBO J 20, 5898-5907.
  3. Tanaka K, Kawakami T, Tateishi K, Yashiroda H, Chiba T.: Control of IkBa proteolysis by the ubiquitin-proteasome pathway., Biochemie. 83(3-4): 351-6. 2001.
  4. Yawata, M., Murata, S., Tanaka, K., Ishigatsubo, Y., and Kasahara, M. (2001): Nucleotide sequence analysis of the approximately 35-kb segment containing interferon-gamma-inducible mouse proteasome activator genes., Immunogenetics 53, 119-129.

2000

  1. Kawahara, H., Kasahara, M., Nishiyama, A., Ohsumi, K., Goto, T., Kishimoto, T., Saeki, Y., Yokosawa, H., Shimbara, N., Murata, S., Chiba, T., Suzuki, K., and Tanaka, K. (2000): Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes., EMBO J 19, 4144-4153.
  2. Takafuji, S., Miyakuni, Y., Nakagawa, T., Shoji, S., Murata, S., Yamamoto, K., and Ito, K. (2000): Effects of human lung fibroblasts on eosinophil degranulation., Allergy 55, 1170-1178.
  3. Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., Nakamura, K., and Taniguchi, T. (2000): T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-g., Nature 408, 600-605.

1999

  1. Furukawa, H., Murata, S., Yabe, T., Shimbara, N., Keicho, N., Kashiwase, K., Watanabe, K., Ishikawa, Y., Akaza, T., Tadokoro, K., Tohma, S., Inoue, T., Tokunaga, K., Yamamoto, K., Tanaka, K., and Juji, T. (1999): Splice acceptor site mutation of the transporter associated with antigen processing-1 gene in human bare lymphocyte syndrome., J Clin Invest 103, 755-758.
  2. Murata, S., Kawahara, H., Tohma, S., Yamamoto, K., Kasahara, M., Nabeshima, Y., Tanaka, K., and Chiba, T. (1999): Growth retardation in mice lacking the proteasome activator PA28g., J Biol Chem 274, 38211-38215.
  3. Urano T, Yashiroda H, Muraoka M, Tanaka K, Hosoi T, Inoue S, Ouchi Y, Toyoshima H.: p57(Kip2) is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor b1., J.Biol. Chem., 274(18):12197-200 1999.