Kadowaki, H., Nagai, A., Maruyama, T., Takami, Y., Fitrah, P.S., Kato, H., Honda, A., Hatta, T., Natsume, T., Sato, T., Kai, H., Ichijo, H. and Nishitoh, H.
Preemptive quality control protects the ER from protein overload via the proximity of ERAD components and SRP.
Cell Rep., 113, 944-956 (2015).

  Miyakawa, K., Matsunaga, S., Kanou, K., Matsuzawa, A., Morishita, R., Kudoh, A., Shindo, K., Yokoyama, M., Sato, H., Kimura, H., Tamura, T., Yamamoto, N., Ichijo, H., Takaori-Kondo, A. and Ryo, A.
ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.
Nat. Commun., 6, 6945 (2015).

  Okazaki, T., Higuchi, M., Takeda, K., Iwatsuki-Horimoto, K., Kiso, M., Miyagishi, M., Yanai, H., Kato, A., Yoneyama, M., Fujita, T., Taniguchi, T., Kawaoka, Y., Ichijo, H. and Gotoh, Y.
The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.
Sci. Signal., 8, ra78 (2015).

  Zhai, J., Zhang, L., Mojsilovic-Petrovic, J., Jian, X., Thomas, J., Homma, K., Schmitz, A., Famulok, M., Ichijo, H., Argon, Y., Randazzo, P. and Kalb, R.
Inhibition of cytohesins protects against genetic models of motor neuron disease.
J. Neurosci., i35, 9086-9105 (2015).

  Fujisawa, T., Yamaguchi, N., Kadowaki, H., Tsukamoto, Y., Tsuburaya, N., Tsubota, A., Takahashi, H., Naguro, I., Takahashi, Y., Goto, J., Tsuji, S., Nishitoh, H., Homma, K. and Ichijo, H.
A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.
Neurobiol. Dis., 82, 478-486 (2015).

  Lee, K.-W., Woo, J.-M., Im, J.-Y., Park, E.-S., He, L., Ichijo, H., Junn, E. and Mouradian M.-M.
Apoptosis Signal Regulating Kinase 1 Modulates the Phenotype of α-Synuclein Transgenic Mice.
Neurobiol. Aging, 36, 519-526 (2015).

  Toyama, K., Koibuchi, N., Hasegawa, Y., Uekawa, K., Yasuda, O., Sueta, D., Nakagawa, T., Ma, M., Kusaka, H., Lin, B., Ogawa, H., Ichijo, H. and Kim-Mitsuyamam S.
ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice.
Sci. Rep., 5, 10844 (2015).

  Tristan, C.A., Ramos, A., Shahani, N., Emiliani, F.E., Nakajima, H., Noeh, C.C., Kato, Y., Takeuchi, T., Noguchi, T., Kadowaki, H., Sedlak, T.W., Ishizuka, K., Ichijo, H. and Sawa, A.
Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an activator of the GAPDH-Siah1 Stress-Signaling Cascade.
J. Biol. Chem., 290, 56-64 (2015).

  Watanabe, T., Sekine, S., Naguro, I., Sekine, Y. and Ichijo, H.
Apoptosis Signal-regulating Kinase 1(ASK1)-p38 pathway-dependent cytoplasmic translocation of the orphan nuclear receptor NR4A2 is required for oxidative stress-induced necrosis.
J. Biol. Chem., 290, 10791-10803 (2015).

Review articles

  Machida, T., Ichijo, H. and Naguro, I.
Regulation of Cellular Signalling by Thioredoxin.
Redox Proteins in Supercomplexes and Signalosomes, Edited by Louro, R.O. and Diaz-Moreno, I., CRC Press, (review article), 255-274 (2015).

  Kamiyama, M., Naguro, I. and Ichijo, H.
In vivo gene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression.
Cancer Sci., (review article), 106, 785-796 (2015).

  Sekine, S. and Ichijo, H.
Mitochondrial proteolysis: Its emerging roles in stress responses.
B.B.A.(review article), 1850, 274-280 (2015).

  Galluzzi, L. et al. 
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.
Cell Death Differ., (review article), 22,58-73 (2015).