Hattori, K., Naguro, I., Okabe, K., Funatsu, T., Furutani, S., Takeda, K. and Ichijo, H.
ASK1 signaling regulates brown and beige adipocyte function.
Nat. Commun., 7, 11158 (2016).

  Sekine, S., Yao, A., Hattori, K., Sugawara, S., Naguro, I., Koike, M., Uchiyama, Y., Takeda, K. and Ichijo, H.
The ablation of mitochondrial protein phosphatase Pgam5 confers resistance against metabolic stress.
EBioMedicine, 5, 82-92 (2016).

  Fujisawa, T., Takahashi, M., Tsukamoto, Y., Yamaguchi, N., Nakoji, M., Endo, M., Kodaira, H., Hayashi, Y., Nishitoh, H., Naguro, I., Homma, K. and Ichijo, H.
The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.
Hum. Mol. Genet., 25, 245-253 (2016).

  Maruyama, J., Kobayashi, Y., Umeda, T., Vandewalle, A., Takeda, K., Ichijo, H. and Naguro, I.
Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway.
Sci. Rep., 6, 18710 (2016).

  Yamaguchi, N., Sekine, S., Naguro, I., Sekine, Y. and Ichijo, H. 
KLHDC10 deficiency protects mice against TNFα-induced systemic inflammation.
PLOS one, 11, e0163118 (2016).

  Koizumi, S., Irie, T., Hirayama, S., Sakurai, Y., Yashiroda, H., Naguro, I., Ichijo, H., Hamazaki, J. and Murata, S.
The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.
eLIFE, 5, e18357 (2016).

  Savitsky, P.†, Krojer, T.†, Fujisawa, T.†, Lambert, JP., Picaud, S., Wang, CY., Shanle, EK., Krajewski, K., Friedrichsen, H., Kanapin, A., Goding, C., Schapira, M., Samsonova, A., Strahl, BD., Gingras, AC., Filippakopoulos, P.
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.
Cell Rep., 17, 2724-2737 (2016).
†These authors contributed equally to this work.

  Picaud, S., Leonards, K., Lambert, JP., Dovey, O., Wells, C., Fedorov, O., Monteiro, O., >Fujisawa, T., Wang, CY., Lingard, H., Tallant, C., Nikbin, N., Guetzoyan, L., Ingham, R., Ley, SV., Brennan, P., Muller, S., Samsonova, A., Gingras, AC., Schwaller, J., Vassiliou, G., Knapp, S., Filippakopoulos, P.
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia
Sci. Adv., 2, e1600760 (2016).

Review articles

  Zhou, X., Naguro, I., Ichijo, H., Watanabe, K.
Mitogen-activated protein kinases as key players in osmotic stress signaling.
Biochem. Biophys. Acta, (review article),1860, 2037-2052 (2016).

  Tsubota, A., Ichijo, H., Homma, K.
Mislocalization, aggregation formation and defect in proteolysis in ALS.
AIMS Molecular Science, (review article), 3, 246-268 (2016).

  Hayashi, Y., Homma, K. and Ichijo, H.
SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.
Adv. Biol. Regul., (review article), 60, 95-104 (2016).